Biologic responses to low level lead exposure.

Low level exposure to lead.

Only five people had used condoms on every occasion and eight people had not used them at all. In my clinic I have been asking girls who have had sex with strangers abroad how often they were able to persuade their partners to use condoms-or even withdrawal. I have so far reached zero out of seven. Although all the girls had asked the men to use condoms, they had refused, and the girls, all of ...

Effects of Low Level of Lead Exposure on Responsiveness of The Rat Isolated Heart to Adrenergics

Background: There are controversial reports about the exact mechanisms of lead-induced hypertension, but many factors such as alteration in the responsiveness of cardiovascular system to endogenous substances including catecholamines could be one of the mechanisms involved. In present study, the effect of exposure to 100 ppm lead acetate by drinking water (in the periods of 4, 8 and 12 weeks)...

Low-Level Prenatal and Postnatal Blood Lead Exposure and Adrenocortical Responses to Acute Stress in Children

BACKGROUND A few recent studies have demonstrated heightened hypothalamic-pituitary-adrenal (HPA) axis reactivity to acute stress in animals exposed to heavy metal contaminants, particularly lead. However, Pb-induced dysregulation of the HPA axis has not yet been studied in humans. OBJECTIVE In this study, we examined children's cortisol response to acute stress (the glucocorticoid product of...

Low-Level Exposure to Lead as a Cardiovascular Risk Factor

Low-level environmental exposure to lead unmasked as silent killer.

Since the dawn of human civilization, lead has been a ubiquitous environmental pollutant.1 In 370 BC, Hippocrates described colic in a lead worker.2 The industrial application of lead continues to the present day. Lead is a toxic metal that, during a lifetime, accumulates in the human body.1 Recent evidence3–6 suggests that lead affects human health at levels of exposure that, until now, were c...