Biologic Activity of Digoxin-Specific Antisera

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Biologic activity of digoxin-specific antisera.

Digoxin-specific antibodies are capable of removing essentially all intracellular digoxin from rat renal cortical slices or from human erythrocytes. In removing digoxin from erythrocytes, these antibodies are capable of reversing an effect of the drug on cellular potassium transport. This study provides direct evidence that antibodies are capable of removing, and thereby reversing the biologica...

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Preparation of specific antisera to digoxin using hapten-[C-17]- and [C-12]-bovine serum albumin conjugates.

*KURAに登録されているコンテンツの利用については,著作権法に規定されている私的使用や引用などの範囲内で行ってください。 *著作権法に規定されている私的使用や引用などの範囲を超える利用を行う場合には,著作権者の許諾を得てください。ただし,著作権者 から著作権等管理事業者(学術著作権協会,日本著作出版権管理システムなど)に権利委託されているコンテンツの利用手続については ,各著作権等管理事業者に確認してください。 Title Preparation of Specific Antisera to Digoxin Using Hapten-[C-17]-and [C12]-Bovine Serum Albumin Conjugates Author(s) Shimada, Kazutake; Mizusawa, Shigenori; Ohkubo, Tadashi; Nambara, ...

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Preparation of Type-specific Antisera to Reoviruses.

Preparation of type-specific antisera to reoviruses has been handicapped by the ubiquitous distribution of these viruses and frequent occurrence of reovirus antibodies in many species of animals. Antisera prepared in rhesus monkeys at this laboratory have shown extensive crossings between the three types (Table 1). Similar crossreactions have been observed in antisera prepared in rabbits (A. M....

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1972

ISSN: 0021-9738

DOI: 10.1172/jci106853