Biohydrogenation of Linolenic Acid to Stearic Acid by the Rumen Microbial Population Yields Multiple Intermediate Conjugated Diene Isomers

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The Journal of Nutrition Nutrient Physiology, Metabolism, and Nutrient–Nutrient Interactions Biohydrogenation of Linolenic Acid to Stearic Acid by the Rumen Microbial Population Yields Multiple Intermediate Conjugated Diene Isomers

The current literature suggests that linolenic acid biohydrogenation converts to stearic acid without the formation of CLA. However, a multitude of CLA were identified in the rumen that are generally attributed to linoleic acid biohydrogenation. This study used a stable isotope tracer to investigate the biohydrogenation intermediates of C-linolenic acid, including CLA. A continuous culture ferm...

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Are conjugated linolenic acid isomers an alternative to conjugated linoleic acid isomers in obesity prevention?

Despite its benefits, conjugated linoleic acid (CLA) may cause side effects after long-term administration. Because of this and the controversial efficacy of CLA in humans, alternative biomolecules that may be used as functional ingredients have been studied in recent years. Thus, conjugated linolenic acid (CLNA) has been reported to be a potential anti-obesity molecule which may have additiona...

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Microbial biohydrogenation of oleic acid to trans isomers in vitro.

Ruminant products are significant sources of dietary trans fatty acids. Trans fatty acids, including various conjugated linoleic acid isomers, have been shown to act as metabolic modifiers of lipid metabolism. Trans fatty acids originate from biohydrogenation of dietary unsaturated fatty acids by gut microbes; however, the exact synthetic pathways are unclear. It was our goal to examine the bio...

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Reticulo-rumen biohydrogenation and the enrichment of ruminant edible products with linoleic acid conjugated isomers

Conjugated linoleic acid (CLA) is presently under extensive research because of its potent anticarcinogenic effects and also because of its effects on the immune system and on lipid metabolism. The biological effects of these acids are briefly reviewed. Ruminant edible products are the richest natural sources of CLA because they are supposed to be mainly derived from rumen biohydrogenation of l...

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The biohydrogenation of alpha-linolenic acid and oleic acid by rumen micro-organisms.

1. alpha-[U-(14)C]Linolenic acid was incubated with the rumen contents of sheep and the metabolic products were characterized by thin-layer chromatography, gas-liquid chromatography and absorption spectroscopy in the ultraviolet and infrared. 2. A tentative scheme for the biohydrogenation route to stearic acid is presented. The main pathway is through diconjugated cis-cis-cis-octadecatrienoic a...

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ژورنال

عنوان ژورنال: The Journal of Nutrition

سال: 2011

ISSN: 1541-6100,0022-3166

DOI: 10.3945/jn.111.138396