منابع مشابه
Biofilm formation by Neisseria meningitidis.
Biofilm formation by the human pathogen Neisseria meningitidis was analyzed. Biofilm-forming meningococcal strains were identified and quantitated by crystal violet staining. Laser scanning confocal microscopy of the meningococcal biofilm revealed variable layers up to 90 microm in thickness. A total of 39 meningococcal isolates were studied; 23 were nasopharyngeal-carriage isolates, and 16 wer...
متن کاملSecreted single-stranded DNA is involved in the initial phase of biofilm formation by Neisseria gonorrhoeae.
Neisseria gonorrhoeae is an obligate human pathogen that colonizes the genital tract and causes gonorrhoea. Neisseria gonorrhoeae can form biofilms during natural cervical infections, on glass and in continuous flow-chamber systems. These biofilms contain large amounts of extracellular DNA, which plays an important role in biofilm formation. Many clinical isolates contain a gonococcal genetic i...
متن کاملThe dam replacing gene product enhances Neisseria gonorrhoeae FA1090 viability and biofilm formation
Many Neisseriaceae do not exhibit Dam methyltransferase activity and, instead of the dam gene, possess drg (dam replacing gene) inserted in the leuS/dam locus. The drg locus in Neisseria gonorrhoeae FA1090 has a lower GC-pairs content (40.5%) compared to the whole genome of N. gonorrhoeae FA1090 (52%). The gonococcal drg gene encodes a DNA endonuclease Drg, with GmeATC specificity. Disruption o...
متن کاملType III Methyltransferase M.NgoAX from Neisseria gonorrhoeae FA1090 Regulates Biofilm Formation and Interactions with Human Cells
Neisseria gonorrhoeae is the etiological factor of the sexually transmitted gonorrhea disease that may lead, under specific conditions, to systemic infections. The gonococcal genome encodes many restriction modification (RM) systems, which main biological role is to defend the pathogen from potentially harmful foreign DNA. However, RM systems seem also to be involved in several other functions....
متن کاملFimbrial haemagglutination by Neisseria gonorrhoeae.
The presence of filamentous appendages distinct from flagella was first discovered in electron microscope preparations by Anderson (1949) and Houwink and van Iterson (1950). Duguid, Smith, Dempster, and Edmunds (1955) confirmed the existence of these structures and suggested the name 'fimbriae' for them; others have called them 'cilia' (Pershina and Vasilieva, 1960) and 'pili' (Brinton, 1959). ...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2005
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.73.4.1964-1970.2005