Biofilm formation, antibiotic resistance, and genome sequencing of a unique isolate Salmonella Typhimurium M3

Salmonella Typhimurium is a zoonotic bacterium that can cause salmonellosis, and the major concerns of S. for food industry are its ability to obtain multidrug resistance form biofilms on food-contact surfaces. In current study, antimicrobial strong biofilm former M3 was assessed by diffusion method. Genome sequencing also applied genes related antibiotic resistance, formation M3. Biofilm-forming capacity found be strain dependent, high number isolates were formers. The biofilm-forming isolate resistant oxacillin, lincomycin, rifampicin, tetracycline, clindamycin, with MIC values 512 μg/mL, 32 16 64 respectively. Genomic annotation showed presence involved in cellulose biosynthesis, curli production, fimbriae flagellar assemble, quorum sensing, chemotaxis, some transcriptional regulators. Antibiotic efflux conferring genes, inactivation target alteration identified. results expand scientific understanding how survive stressful conditions industry.