Biodosimetry and assessment of radiation dose
نویسندگان
چکیده
منابع مشابه
Radiation Dose Estimation by Automated Cytogenetic Biodosimetry.
The dose from ionizing radiation exposure can be interpolated from a calibration curve fit to the frequency of dicentric chromosomes (DCs) at multiple doses. As DC counts are manually determined, there is an acute need for accurate, fully automated biodosimetry calibration curve generation and analysis of exposed samples. Software, the Automated Dicentric Chromosome Identifier (ADCI), is presen...
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The most frequently used and the best established method of biological dosimetry at present is the dicentric chromosome assay, which is poorly suitable for a mass casualties scenario. This gives rise to the need for the development of new, high-throughput assays for rapid identification of the subjects exposed to ionizing radiation. In the present study, we tested the usefulness of gene express...
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Background: Hot lab is a specially designed room in a nuclear medicine hospital where the radiopharmaceuticals are delivered, stored and prepared for dispensing. 99Mo/99mTc-generator is the major source in the hot lab used for various medical imaging. It is important to maintain a standard for hot lab procedures to optimize the patient care and minimize radiation exposure to all nuclear medicin...
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Introduction: The rapid use of computed tomography (CT) scan is of great concern, due to increase in patients’ dose. Optimization of CT protocol is a vital issue in dose reduction. This study aimed to optimize radiation dose in cranial CT and assess modifications in image quality under radiation dose reduction. Material and Methods: A poly(me...
متن کاملExpedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
Biological radiation dose can be estimated from dicentric chromosome frequencies in metaphase cells. Performing these cytogenetic dicentric chromosome assays is traditionally a manual, labor-intensive process not well suited to handle the volume of samples which may require examination in the wake of a mass casualty event. Automated Dicentric Chromosome Identifier and Dose Estimator (ADCI) soft...
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ژورنال
عنوان ژورنال: Reports of Practical Oncology & Radiotherapy
سال: 2011
ISSN: 1507-1367
DOI: 10.1016/j.rpor.2011.06.003