Biocontrol Potential, Genome and Nonribosomal Peptide Synthetase Gene Expression of Bacillus velezensis 2211

Members of the genus Bacillus produced a diverse group antimicrobial compounds. Here, we presented antifungal activity and genome sequence analysis sp. 2211, potential plant-growth-promoting bacterium. Bacterial supernatants from strain 2211 cultures in nutrient broth (NB) potato dextrose (PDB) suppressed mycelial growth Pyricularia oryzae, Colletotrichum aenigma, fructicola Fusarium oxysporum. The were also able to suppress spore germination these fungi, except for F. However, supernatant PDB displayed significantly higher inhibition than NB. Additionally, reduced disease severity caused by P. oryzae on rice seedlings. was sequenced. highest digital DNA-DNA hybridization (80.1%) average nucleotide identity (97.57%) levels indicated that member species velezensis. phylogenomic showed it clustered with B. velezensis NRRL B-41580T, KACC 13105 subsp. plantarum FZB42T. gene expression up-regulation nonribosomal peptide synthetase (NRPS) genes bmyA, fenB dhbE PDB, compared This work demonstrated culture media affected antagonistic possibly through modification NRPS biosynthesis genes.