Biocompatibility of a decellularized liver scaffold in studies in vitro
نویسندگان
چکیده
منابع مشابه
Orthotopic transplantation of decellularized liver scaffold in mice.
End-stage liver disease is a life threatening health problem to millions of people worldwide. Orthotopic liver transplantation is the only therapy for the definitive cure at the present time. However, persistent shortage in donor organs limits the opportunity for patients to receive this treatment. Liver tissue engineering aims to overcome this restriction by generating functional tissue constr...
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In vitro histological investigation of interactions between rat decellularized large intestine scaffold and human adipose derived mesenchymal stem cells
The aim of this study was to investigate the interactions between rat intestine decellularized scaffold and human adipose derived mesenchymal stem cells. Rat large intestine was dissected in fragments and decellularized by physicochemical methods. The scaffolds were loaded by human adipose derived mesenchymal stem cells expressing green fluorescent protein. Microscopic sections were prepared fr...
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Liver synthetic and metabolic function can only be optimised by the growth of cells within a supportive liver matrix. This can be achieved by the utilisation of decellularised human liver tissue. Here we demonstrate complete decellularization of whole human liver and lobes to form an extracellular matrix scaffold with a preserved architecture. Decellularized human liver cubic scaffolds were rep...
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ژورنال
عنوان ژورنال: Journal of the Belarusian State University. Biology
سال: 2021
ISSN: 2617-3964,2521-1722
DOI: 10.33581/2521-1722-2021-1-20-27