BIOCHEMISTRY OF MYOGLOBIN

Myoglobin expression: early induction and subsequent modulation of myoglobin and myoglobin mRNA during myogenesis.

We showed that myoglobin gene transcription and the appearance of myoglobin occur very early in myogenesis, in both humans and mice. In contrast to the contractile protein genes, there is a subsequent increase of 50- to 100-fold in myoglobin mRNA and protein levels during later muscle development. Myoglobin and myoglobin mRNA are present at elevated levels in fetal heart and are also detectable...

The 15th Iranian National Congress of Biochemistry & 6th International Congress of Biochemistry and Molecular Biology

Editor Note – Biochemistry & Analytical Biochemistry

Biochemistry is the study of structures, functions and interactions of biomolecules, such as carbohydrates, nucleic acids, proteins, lipids, etc. and their metabolisms. Advancements in biochemistry helps in the advancement of different fields like agriculture, medicine, nutrition, etc., which are directly related to it. Combination of biochemical techniques with techniques and ideas of genetics...

Myoglobin-Catalyzed Olefination of Aldehydes.

The olefination of aldehydes constitutes a most valuable and widely adopted strategy for constructing carbon-carbon double bonds in organic chemistry. While various synthetic methods have been made available for this purpose, no biocatalysts are known to mediate this transformation. Reported herein is that engineered myoglobin variants can catalyze the olefination of aldehydes in the presence o...

Case Study: Myoglobin