Biochemical and Structural Analysis of Helix pomatia Agglutinin
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چکیده
منابع مشابه
Biochemical and Structural Analysis of Helix Pomatia Agglutinin (hpa): a Hexameric Lectin with a Novel Fold*
AGGLUTININ (HPA): A HEXAMERIC LECTIN WITH A NOVEL FOLD* Jean-Frederic Sanchez, Julien Lescar, Valérie Chazalet, Aymeric Audfray, Jean Gagnon, Richard Alvarez, Christelle Breton, Anne Imberty & Edward P. Mitchell From Centre de Recherches sur les Macromolécules Végétales, CNRS (affiliated with Université Joseph Fourier), Grenoble, France, School of Biological Sciences, Nanyang Technological Univ...
متن کاملBiochemical and structural analysis of Helix pomatia agglutinin. A hexameric lectin with a novel fold.
Helix pomatia agglutinin (HPA) is a N-acetylgalactosamine (GalNAc) binding lectin found in the albumen gland of the roman snail. As a constituent of perivitelline fluid, HPA protects fertilized eggs from bacteria and is part of the innate immunity system of the snail. The peptide sequence deduced from gene cloning demonstrates that HPA belongs to a family of carbohydrate-binding proteins recent...
متن کاملBiochemical and electronmicroscopic investigations on Helix pomatia collagen.
The skin of Helix pomatia was investigated by biochemical methods and electronmicroscope. Biochemical investigations showed that Helix pomatia collagen represents a methionine-lacking collagen resistant to CNBr-cleavage. Electron microscopic studies showed a cross striation pattern of 53--57 nm.
متن کاملLectin histochemical study of cell surface glycoconjugate in gastric carcinoma using helix pomatia agglutinin.
Altered glycosylation of proteins in cancer cells is one of the main processes responsible for anaplasia, invasion and metastatic potential of neoplastic cells. Lectins are nonimmunogenetic compounds which specifically detect certain terminal sugars of glycoconjugates. The aim of the present study was to identify the N-acetylgalactosamine (GalNac) containing glycoconjugates in cancer cells in a...
متن کاملlectin histochemical study of cell surface glycoconjugate in gastric carcinoma using helix pomatia agglutinin
altered glycosylation of proteins in cancer cells is one of the main processes responsible for anaplasia, invasion and metastatic potential of neoplastic cells. lectins are nonimmunogenetic compounds which specifically detect certain terminal sugars of glycoconjugates. the aim of the present study was to identify the n-acetylgalactosamine (galnac) containing glycoconjugates in cancer cells in a...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2006
ISSN: 0021-9258
DOI: 10.1074/jbc.m603452200