Bioassay-Guided Identification of Bioactive Compounds from Senna alata L. against Methicillin-Resistant Staphylococcus aureus
نویسندگان
چکیده
Senna alata (Linn) Roxb. plant is widely used to manage various infections in folkloric medicine. Methicillin-resistant Staphylococcus aureus (MRSA) infection continues be a major global public health problem. This study aims investigate the bioactive components of S. leaves active against MRSA. The were sequentially extracted and fractionated using standard methods screened for activities diethyl ether thin layer chromatography (TLC) spot was subjected infrared (IR) gas chromatography-mass spectroscopic (GC-MS) studies. aqueous extract fraction elicited highest activity GC-MS analysis produced 15 eluates; only sub-fraction 13 effective. TLC revealed three spots; second activity. result showed six peaks. spectral results peak 3 match data from IR study, suggestive 9-octadecenoic acid methyl ester. possess compounds closely related ester with potent antibacterial
منابع مشابه
bioassay guided fractionation of an anti-methicillin-resistant staphylococcus aureus flavonoid from bromus inermis leyss inflorescences
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ژورنال
عنوان ژورنال: Applied microbiology
سال: 2021
ISSN: ['0003-6919']
DOI: https://doi.org/10.3390/applmicrobiol1030034