Bioassay-Directed Isolation of Active Compounds with Antiyeast Activity from a Cassia fistula Seed Extract

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Bioassay-directed isolation of active compounds with antiyeast activity from a Cassia fistula seed extract.

BACKGROUND AND OBJECTIVE Cassia fistula L belongs to the family Leguminosae, and it is one of the most popular herbal products in tropical countries. C. fistula seeds have been used as a herbal medicine and have pharmacological activity which includes anti-bacterial, anti-fungal, and antioxidant properties. The goal of this study was to identify compounds from C. fistula seeds which are respons...

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Preliminary isolation and in vitro antiyeast activity of active fraction from crude extract of Gracilaria changii

OBJECTIVE To isolate the active fraction from crude extract of Gracilaria changii and to determine its in vitro antifungal activity. MATERIALS AND METHODS The active fraction was isolated from the crude extract of G. changii by various purification procedures such as column chromatography, thin layer chromatography, bioauthograph etc. The in vitro antifungal activity (Candida albicans) of the...

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Acute oral toxicity of methanolic seed extract of Cassia fistula in mice.

BACKGROUND AND OBJECTIVE Cassia fistula is widely used in traditional medicine to treat various types of ailments. The evaluation of toxic properties of C. fistula is crucial when considering public health protection because exposure to plant extracts can result in undesirable effects on consumers. Hence, in this study the acute oral toxicity of C. fistula seeds extract was investigated in mice...

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The in vitro and in silico analysis of Rubus fairholmianus acetone extract for antioxidant, antiproliferative, and anti-inflammatory activity led to the isolation of six compounds. Amongst all the six isolated compounds tested, 1-(2-hydroxyphenyl)-4-methylpentan-1-one (compound 1) and 2-[(3-methylbutoxy) carbonyl] benzoic acid (compound 2) were found to be more active in inhibiting BRCA and COX...

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In vitro, in situ and in vivo studies on the anticandidal activity of Cassia fistula seed extract.

Cassia fistula seeds have many therapeutic uses in traditional medicine practice. The present investigation was undertaken to demonstrate the anticandidal activity of the C. fistula seed extract at ultra-structural level through transmission electron microscope (TEM) and scanning electron microscope (SEM) observations. The effect of seed extract on the growth profile of the Candida albicans was...

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ژورنال

عنوان ژورنال: Molecules

سال: 2011

ISSN: 1420-3049

DOI: 10.3390/molecules16097583