Bioadhesive Properties of Gantrez Nanoparticles
نویسندگان
چکیده
منابع مشابه
Bioadhesive properties of Gantrez nanoparticles.
Bioadhesive nanoparticles have been proposed as carriers for the oral delivery of poorly available drugs and facilitate the use of this route. This work summarises some experiments describing the bioadhesive potential of Gantrez nanoparticles fluorescently labeled with rhodamine B isothiocyanate. The adhesive potential of Gantrez was found to be stronger when folded as nanoparticles than in the...
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Gantrez AN (a copolymer between methyl vinyl ether and maleic anhydride) nanoparticles were prepared by the solvent displacement method, and different dextrans with different molecular weight were associated to these nanoparticles in order to modify their surface characteristics. The resulting nanoparticles were characterized in terms of size, zeta potential, amount of dextran associated and de...
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Oral delivery is the most convenient and desired way for drug delivery. The major factor determinant for bioavailability of orally administered drug is the membrane permeability and drug solubility in the intestinal lumen. Many drugs show bioavailability problems due to their low water solubility, slow dissolution rate and instability in the gastrointestinal tract. One possibility to enhance dr...
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ژورنال
عنوان ژورنال: Molecules
سال: 2005
ISSN: 1420-3049
DOI: 10.3390/10010126