Binary fate decisions in differentiating neurons
نویسندگان
چکیده
منابع مشابه
Binary fate decisions in differentiating neurons.
Neural cell fate programs must generate an enormous number of neurons with distinct adult functions. The decision to choose one neuronal subtype from two alternatives--a binary fate decision--is one way to diversify neuronal subtypes during nervous system development. Recent progress has been made in describing the genetic programs that define late-stage neuronal identity. Here, we review mecha...
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The Wnt/β-catenin pathway plays key roles during animal development. In several species, β-catenin is used in a reiterative manner to regulate cell fate diversification between daughter cells following division. This binary cell fate specification mechanism has been observed in animals that belong to very diverse phyla: the nematode Caenorhabditis elegans, the annelid Platynereis, and the ascid...
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ژورنال
عنوان ژورنال: Current Opinion in Neurobiology
سال: 2010
ISSN: 0959-4388
DOI: 10.1016/j.conb.2009.11.002