منابع مشابه
Bilirubin, a curse and a boon.
B oth hydrophobic bile salts 2 and unconjugated bilirubin (UCB) induce apoptosis in cultured cells at moderately elevated concentrations and cell necrosis at higher concentrations. Retention of bile salts in cholestasis is believed to cause secondary damage to hepatocytes, and retention of UCB in severe neonatal jaundice is known to cause bilirubin encephalopathy. For both agents, the cytotoxic...
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Millions of DNA-damaging lesions occur every day in each cell of our bodies due to various stresses. The failure to detect and accurately repair these lesions can give rise to cells with high levels of endogenous DNA damage, deleterious mutations, or genomic aberrations. Such genomic instability can lead to the activation of specific signaling pathways, including the DNA damage response (DDR) p...
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When accidental bequests signal otherwise unobservable individual characteristics such as productivity and longevity, the population should be partitioned into two groups: those who do not receive an inheritance those who do. The rst tagged group gets a second-best tax à la Mirrlees; the second group, when its type is fully revealed, a rst-best tax schedule. Receiving an inheritance makes hig...
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ژورنال
عنوان ژورنال: Gut
سال: 2003
ISSN: 0017-5749
DOI: 10.1136/gut.52.12.1668