Bilateral acute renal infarction secondary to methylene tetrahydrofolate reductase A1298C and PAI-1 mutation
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منابع مشابه
Bilateral renal vein thrombosis secondary to methylene tetrahydrofolate reductase mutation: a rare case
Bilateral renal vein thrombosis secondary to methylene tetrahydrofolate reductase mutation: a rare case To the Editor, Renal vein thrombosis (RVT) is a rare but serious complication that is associated with many systemic disorders [1]. Thromboembolic complications, especially RVT, are frequent in nephrotic syndrome and are very prevalent in membranous nephropathy [1]. Trauma, oral contraceptives...
متن کاملSegmental renal artery thrombosis secondary to methylene tetrahydrofolate reductase mutation: an unusual presentation.
Methylene tetrahydrofolate reductase (MTHFR) is an enzyme involved in the metabolism of homocysteine to methionine, and folic acid is an essential cofactor. Mutations in the MTHFR gene lead to hyperhomocysteinemia and vascular thrombosis. Heterozygous mutation involving a single nucleotide polymorphism in the MTHFR gene leading to vascular thrombosis is very rare. We present a case of segmental...
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Modifiable risk factors for CHD include high blood pressure, high blood cholesterol, smoking, obesity, physical inactivity, diabetes, and stress. When a patient presents with the typical features of CHD (like ours) but do not have the modifiable risk factors, genetic causes should be considered. A limited number of genetic variants are proven to be independent risk factors for thromboembolism. ...
متن کاملMethylene-tetrahydrofolate reductase contributes to allergic airway disease
RATIONALE Environmental exposures strongly influence the development and progression of asthma. We have previously demonstrated that mice exposed to a diet enriched with methyl donors during vulnerable periods of fetal development can enhance the heritable risk of allergic airway disease through epigenetic changes. There is conflicting evidence on the role of folate (one of the primary methyl d...
متن کاملHyperhomocysteinemia, low folate and vitamin B12 concentrations, and methylene tetrahydrofolate reductase mutation in cerebral venous thrombosis.
BACKGROUND AND PURPOSE Elevated plasma levels of homocysteine are associated with an increased risk of deep-vein thrombosis. Through a case-control study, we examined the potential association among homocysteine, folate and vitamin B12 levels, and the common C677-->T mutation in the methylene tetrahydrofolate reductase (MTHFR) gene in patients with cerebral venous thrombosis (CVT). METHODS Fo...
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ژورنال
عنوان ژورنال: Indian Journal of Nephrology
سال: 2020
ISSN: 0971-4065
DOI: 10.4103/ijn.ijn_65_20