Biexponential diffusion decay in formalin-fixed prostate tissue: Preliminary findings
نویسندگان
چکیده
منابع مشابه
Biexponential diffusion decay in formalin-fixed prostate tissue: preliminary findings.
Magnetic resonance microimaging was used to measure diffusion decay over an extended b-factor range in a formalin-fixed normal prostate sample and a Gleason pattern 3+4 cancer tissue sample. The coefficients of biexponential fits to diffusion decay data from 1600 voxels of dimension 160 × 160 × 160 μm(3) in each sample were correlated with underlying epithelial and stromal compartment partial v...
متن کاملMicroscopic diffusion anisotropy in formalin fixed prostate tissue: preliminary findings.
Diffusion tensor microimaging at 16.4 T with 40 μm isotropic voxels was used to investigate anisotropic water diffusion in prostate tissue at spatial resolution approaching the cellular scale. Nine normal glandular tissue samples were collected from the peripheral zone of six formalin fixed radical prostatectomy specimens. Fibromuscular stromal tissue exhibited microscopic diffusion anisotropy ...
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Diffusion tensor microimaging with 40 μm isotropic voxels at 16.4 T was used to investigate compartmentation of water diffusion and biexponential diffusion decay in formalin fixed prostate tissue. Tissue samples (~28 mm) were similar in volume to a typical prostate DWI voxel in vivo and were imaged with ~400,000 voxels. The bulk mean diffusivity (‘ADC’) of epithelial, stromal, and ductal/acinal...
متن کاملMicroscopic Diffusion Anisotropy in Formalin Fixed Prostate Tissue
Diffusion tensor microimaging at 16.4 T with 40µm isotropic voxels was to investigate anisotropic water diffusion in prostate tissue at spatial resolution approaching the cellular scale. Nine normal tissue and two cancer samples were collected from the peripheral zone of six formalin fixed radical prostatectomy specimens. Fibromuscular stromal tissue exhibited microscopic diffusion anisotropy (...
متن کاملMicroscopic diffusion properties of fixed breast tissue: Preliminary findings.
PURPOSE To investigate the microscopic diffusion properties of formalin-fixed breast tissue. METHODS Diffusion microimaging was performed at 16.4T with 40-μm isotropic voxels on two normal and two cancer tissue samples from four patients. Results were correlated with histology of the samples. RESULTS Diffusion-weighted images and mean diffusivity maps demonstrated distinct diffusivity diffe...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2011
ISSN: 0740-3194
DOI: 10.1002/mrm.23291