Bias between MNI and Talairach coordinates analyzed using the ICBM-152 brain template

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Bias between MNI and Talairach coordinates analyzed using the ICBM-152 brain template.

MNI coordinates determined using SPM2 and FSL/FLIRT with the ICBM-152 template were compared to Talairach coordinates determined using a landmark-based Talairach registration method (TAL). Analysis revealed a clear-cut bias in reference frames (origin, orientation) and scaling (brain size). Accordingly, ICBM-152 fitted brains were consistently larger, oriented more nose down, and translated sli...

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Many functional imaging studies match their data to a brain template from the Monteal Neurological Institute (MNI). It is common for such studies to report activation coordinates and estimated Brodmann areas (BAs) in terms of the 1988 atlas of Talairach and Tournoux. This can be problematic, as the brains in the Talairach atlas and MNI template differ significantly in shape and size. This poste...

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Spatial normalization of neuroimaging data is a standard step when assessing group effects. As a result of divergent analysis procedures due to different normalization algorithms or templates, not all published coordinates refer to the same neuroanatomical region. Specifically, the literature is populated with results in the form of MNI or Talairach coordinates, and their disparity can impede t...

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ژورنال

عنوان ژورنال: Human Brain Mapping

سال: 2007

ISSN: 1065-9471,1097-0193

DOI: 10.1002/hbm.20345