Beyond the Gail Model: Lobular Involution May Help Refine Breast Cancer Risk Assessment
نویسندگان
چکیده
منابع مشابه
Breast cancer risk assessment in Iranian women by Gail model
Abstract Background: Due to the high incidence of breast cancer and the effect of its early diagnosis on decreasing morbidity and mortality, we used the Gail model to study breast cancer risk in Iranian women. Methods: This study was done in a simple randomized way. Participants were 2000 Iranian women older than 35 years old. The questionnaire consisted of demographic data such a...
متن کاملbreast cancer risk assessment in iranian women by gail model
abstract background: due to the high incidence of breast cancer and the effect of its early diagnosis on decreasing morbidity and mortality, we used the gail model to study breast cancer risk in iranian women. methods: this study was done in a simple randomized way. participants were 2000 iranian women older than 35 years old. the questionnaire consisted of demographic data such as age, rac...
متن کاملperformance of the gail model for breast cancer risk assessment in iranian women
background: the gail model has been widely used for estimation of absolute risk of breast cancer development. the original model and most of the validation studies have been performed among western populations and controversial results have been reported regarding the applicability of this model in asian populations. our aim was to investigate the performance of this model in iranian women. met...
متن کاملLobular involution: the physiological prevention of breast cancer.
It truly is a remarkable event when traditional pathologic observations lead to new ideas about the prevention of cancer. In this issue of the Journal , Milanese et al. (1) , through a histologic review of breast biopsy specimens, show that the extent of age-related lobular involution is strongly associated with a reduced risk of breast cancer. Breast cancer risk decreased with increasing exten...
متن کاملIndependent Association of Lobular Involution and Mammographic Breast Density With Breast Cancer Risk
BACKGROUND Lobular involution, or age-related atrophy of breast lobules, is inversely associated with breast cancer risk, and mammographic breast density (MBD) is positively associated with breast cancer risk. METHODS To evaluate whether lobular involution and MBD are independently associated with breast cancer risk in women with benign breast disease, we performed a nested cohort study among...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2009
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djn505