Bevacizumab: Off-label use in ophthalmology
نویسندگان
چکیده
منابع مشابه
[Off-label prescribing: scientific analysis taking the use of bevacizumab in ophthalmology as an example].
Off-label prescribing poses specific technical/scientific, professional and ethical problems. In this study we carry out a technical and scientific analysis of the off-label prescribing using a current, clinical and economically relevant example: the paradigmatic case of the use of bevacizumab in ophthalmologic pathologies for which it has no formal indication. We conducted a systematic review ...
متن کاملOff-label use of intravitreal bevacizumab (Avastin) for salvage treatment in progressive threshold retinopathy of prematurity.
PURPOSE To report the short term anatomic response of intravitreal bevacizumab (Avastin, Genentech) as salvage treatment in progressive retinopathy of prematurity (ROP) in a small series of patients. METHODS The study included five eyes of three patients with progressive ROP despite peripheral laser ablation. Patients received intravitreal injections of bevacizumab (Avastin, Genentech). RetCa...
متن کاملOff-label use of vaccines.
This article reviews the off-label recommendations and use of vaccines, and focuses on the differences between the labelled instructions on how to use the vaccine as approved by the regulatory authorities (or "label"1), and the recommendations for use issued by public health advisory bodies at national and international levels. Differences between public health recommendations and the product l...
متن کامل[Off-label use of intravitreal bevacizumab for severe retinopathy of prematurity].
OBJECTIVE To examine the quality of evidence and the variability in the off-label use of intravitreal bevacizumab for retinopathy of prematurity (ROP). METHODS A wide review of the literature was performed using Pubmed, Medline, and Cochrane database, using the words vascular endothelial growth factor (VEGF), retinopathy of prematurity, treatment and bevacizumab. RESULTS Case reports, case ...
متن کاملA systematic analysis of the off-label use of bevacizumab for severe retinopathy of prematurity.
PURPOSE To examine the quality of evidence and the variability in the off-label use of bevacizumab (Avastin; Genentech Inc, South San Francisco, California, USA) in the treatment of retinopathy of prematurity (ROP) and to discuss the implications for the design of future randomized controlled trials. DESIGN Systematic literature review. METHODS A systematic review of the literature indexed ...
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ژورنال
عنوان ژورنال: Indian Journal of Ophthalmology
سال: 2007
ISSN: 0301-4738
DOI: 10.4103/0301-4738.36474