Bevacizumab in high-grade glioma patients following intraparenchymal hemorrhage
نویسندگان
چکیده
منابع مشابه
RapidArc: Initial experience in high grade glioma
Background: Identify the optimal technique of radiotherapy for patients with high grade glioma. Our initial year of experience with RapidArc radiation therapy. Materials and Methods: Planning CT scans of 50 patients with grade IV glioma were reviewed and three plan sets by 3D Conformal Radiotherapy (3DCRT), Intensity Modulated Radiotherapy (IMRT) and Rapid Arc (RA) were generated and the plans ...
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BACKGROUND Angiogenesis inhibition is a rational treatment strategy for high-grade glioma (HGG). Combined antiangiogenic therapy and chemotherapy could be beneficial, taking advantage of different mechanisms of antitumour activity of both therapies. We carried out a phase I-II clinical trial with the combination of bevacizumab and continuous dose-intense temozolomide (TMZ) for patients with a r...
متن کاملBevacizumab salvage therapy following progression in high-grade glioma patients treated with VEGF receptor tyrosine kinase inhibitors.
Agents targeting the vascular endothelial growth factor (VEGF) pathway are being used with increasing frequency in patients with recurrent high-grade glioma. The effect of more than one antiangiogenic therapy given in succession has not been established. We reviewed the efficacy of bevacizumab, a VEGF-A monoclonal antibody, in patients who progressed following prior therapy with VEGF receptor t...
متن کاملThromboembolism in patients with high-grade glioma.
OBJECTIVE To identify factors related to increased or decreased risk of thromboembolism (TE) in patients with high-grade glioma. DESIGN We performed a retrospective analysis of 64 patients enrolled in two prospective clinical trials of chemotherapy and radiation therapy for newly diagnosed high-grade glioma. MATERIAL AND METHODS The 64 patients were 18 years of age or older and had histolog...
متن کاملrapidarc: initial experience in high grade glioma
background: identify the optimal technique of radiotherapy for patients with high grade glioma. our initial year of experience with rapidarc radiation therapy. materials and methods: planning ct scans of 50 patients with grade iv glioma were reviewed and three plan sets by 3d conformal radiotherapy (3dcrt), intensity modulated radiotherapy (imrt) and rapid arc (ra) were generated and the plans ...
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ژورنال
عنوان ژورنال: Neuro-Oncology Practice
سال: 2016
ISSN: 2054-2577,2054-2585
DOI: 10.1093/nop/npw008