منابع مشابه
The Survey of Genes Encoding Beta-Lactamases, in Escherichia Coli Resistant to Beta-Lactam and Non-Beta-Lactam Antibiotics
Objective(s) Resistance to the new generation of cephalosporins which is mediated by Extended-Spectrum beta-lactamases (ESBLs) has been found among Escherichia coli isolates throughout the world. These resistance genes and their producers, the micro-organisms carrying beta-lactamases, are responsible for serious clinical and therapeutic problems among inpatients and it is necessary to pay more...
متن کاملBeta-Lactam Antibiotics and Vancomycin Beta-lactam antibiotics
Anti-bacterial drugs have “selective toxicity”, that is they interact with a target present on the bacterial cell, the prokaryote, that is not present in the mammalian host, the eukaryote. For the ß-lactam drugs, this target is the cell wall. Mammalian cells lack cell walls, which for the bacteria are a critically important barrier protecting the organism from not only the vagaries of osmotic s...
متن کاملBeta lactam hypersensitivities
Background Allergic reactions to drugs are often unpredictable and can lead to serious side effects such as anaphylactic shock. According to the hapten hypothesis, any drug with a molecular weight lower than 1000 daltons cannot induce an immune response by itself and must be bound to a protein. Antigen presenting cells, such as dendritic cells (DC), internalize hapten-protein conjugates and dig...
متن کاملBeta-lactam and CMV induced drug hypersensitivity syndrome
Beta-lactam antibiotics are one of the most common causes of drug allergic reactions. These reactions may be manifested by a concomitant viral infections caused by HIV, CMV, HHV6 or EBV, especially in children and less common in adults. The aim of our study is to present the case of adult patient with drug hypersensitivity syndrome caused by beta-lactams and manifestation of viral infection. A ...
متن کاملChemistry of Beta Lactam Antibiotics
Humans have been plagued with the threat of bacterial infection since before the dawn of recorded history, and have thus always had a keen interest in finding a suitable treatment for these maladies. In the early part of the 19th century, colonial Americans were fearful of death by bacterial infections that are now considered routine, and usually inquired about one another's health in their let...
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ژورنال
عنوان ژورنال: Journal of the Intensive Care Society
سال: 2016
ISSN: 1751-1437
DOI: 10.1177/1751143715594628