Beta-caryophyllene is a dietary cannabinoid
نویسندگان
چکیده
منابع مشابه
Beta-caryophyllene is a dietary cannabinoid.
The psychoactive cannabinoids from Cannabis sativa L. and the arachidonic acid-derived endocannabinoids are nonselective natural ligands for cannabinoid receptor type 1 (CB(1)) and CB(2) receptors. Although the CB(1) receptor is responsible for the psychomodulatory effects, activation of the CB(2) receptor is a potential therapeutic strategy for the treatment of inflammation, pain, atherosclero...
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Beta-caryophyllene (BC) is a chemical found in the essential oil of numerous plants which have shown various biomedical properties. In the present investigation we examined for the first time its genotoxic capacity in vivo by evaluating its potential to induce micronuclei in mouse. In a first assay we administered three doses of the compound once, and in a second assay, we administered three do...
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The widespread plant volatile beta-caryophyllene (BCP) was recently identified as a natural selective agonist of the peripherally expressed cannabinoid receptor 2 (CB₂). It is found in relatively high concentrations in many spices and food plants. A number of studies have shown that CB₂ is critically involved in the modulation of inflammatory and neuropathic pain responses. In this study, we ha...
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Beta-caryophyllene (BCP) and docosahexaenoic acid (DHA) are components of several plants with documented anti-inflammatory and analgesic effects in animal pain models. In the present study, in vitro and in vivo tests were carried out to evaluate their effects, alone or in combination, during long-lasting administration in a model of persistent pain. IR spectra of the two compounds were obtained...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424
DOI: 10.1073/pnas.0803601105