Beta-adrenoceptors in human lung, bronchus and lymphocytes.
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چکیده
منابع مشابه
Beta 2-adrenoceptors in human lung and peripheral mononuclear leukocytes of untreated and terbutaline-treated patients.
Beta 2-adrenoceptor agonists act against bronchoconstriction by stimulating beta 2-adrenoceptors in bronchial smooth muscle. However, tachyphylaxis has been argued to occur because of beta 2-adrenoceptor down-regulation following therapy with beta 2-adrenergic agents. To investigate receptor alterations, human peripheral mononuclear leukocytes are frequently used, since human lung tissue is not...
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One hundred and twenty years after the description of extracts from the adrenal medulla, the use of beta-blockers and beta-agonists evolved from antianginal drugs and tocolytics to ligand-directed signaling. Beta-blockers in the fields of obstetrics and gynecology have so far been limited to the consideration of continuing treatment of disorders of the cardiovascular system and other dysfunctio...
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The lung scans of 101 patients with carcinoma of the bronchus have been compared with the bronchoscopic and radiographic findings. As the tumour approaches the hilum as judged by bronchoscopy or the chest radiograph the relative perfusion of the affected lung decreases. When the relative perfusion of the affected lung is less than one third of the total the tumour is likely to be inoperable. Th...
متن کاملLung perfusion patterns in carcinoma of bronchus.
Recent developments in nuclear medicine have made the measurement of ventilation or perfusion in an individual lung or lobe a relatively simple procedure. Two main techniques are currently available. In one radioactive gases are used, either inhaled or injected intravenously in solution (Dyson et al., 1960; West et al., 1961 ; Ball et d., 1962), the other uses isotopically labelled microemboli ...
متن کاملUpregulation of beta(3)-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium.
BACKGROUND Contrary to beta(1)- and beta(2)-adrenoceptors, beta(3)-adrenoceptors mediate a negative inotropic effect in human ventricular muscle. To assess their functional role in heart failure, our purpose was to compare the expression and contractile effect of beta(3)-adrenoceptors in nonfailing and failing human hearts. METHODS AND RESULTS We analyzed left ventricular samples from 29 fail...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1980
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1980.tb01783.x