Beta-Adrenergic Receptors and Mechanisms in Asthma: The New Long-Acting Beta-Agonists
نویسندگان
چکیده
منابع مشابه
Safety of Long - Acting Beta - Agonists in Asthma ASTHMA THERAPY
THE EUROPEAN JOURNAL OF RESPIRATORY MEDICINE VOL I ISSUE I Although there was no attempt to determine degree of adherence with ICS at randomisation or persistence in their use during the course of the study, no significant differences were seen for primary events and asthma-related events, including deaths in the total population of patients receiving ICS at baseline. However, in the total popu...
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n engl j med 375;9 nejm.org September 1, 2016 889 globulin mucin 3 (TIM-3) or other checkpoints,4 and recently identified mechanisms of primary resistance to PD-1–PD-L1 blockade, which include transcriptional signatures in the tumor microenvironment (innate anti–PD-1 resistance signature, or IPRES5) and the presence of somatic differences in tumor cells (constitutive activation of β-catenin6 or...
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The LABAs have played an important role in the management of asthma over the past decade. They are of clear benefit in reducing asthma-related symptoms and improving lung function when used in combination with an anti-inflammatory agent. Studies have shown, however, that their use has been associated with various negative outcomes, which has led to a restricted indication for salmeterol xinafoa...
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New long-acting beta 2-adrenoceptor agonists, formoterol and salmeterol, may soon appear in several European countries for treatment of asthma. This review examines currently available information and compares the basic pharmacology and describes the clinical effects of these new drugs. The long duration of bronchodilation seen in clinical studies seems to be similar, whereas in isolated tissue...
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ژورنال
عنوان ژورنال: Allergology International
سال: 1996
ISSN: 1323-8930
DOI: 10.2332/allergolint.45.13