Bet on NETs! Or on How to Translate Basic Science into Clinical Practice
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چکیده
منابع مشابه
Bet on NETs! Or on How to Translate Basic Science into Clinical Practice
Neutrophil extracellular traps (NETs) comprise neutrophil DNA, citrullinated (deiminated) histones, and proteases (1, 2). NET formation in vivo mostly occurs at the sites of inflammation. Neutrophils, adhering to the endothelium or after extravasation, generate NETs upon interaction with microbes, activated platelets, cytokines, alarmins, such as high-mobility group box 1 (HMGB1), or uric acid....
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2016
ISSN: 1664-3224
DOI: 10.3389/fimmu.2016.00417