Benzopyranoisoxazolidines: Useful Chiral Auxiliaries for Asymmetric Synthesis.
نویسندگان
چکیده
منابع مشابه
Chiral Auxiliaries in Asymmetric Synthesis
Background The use of chiral auxiliaries in the synthesis of enantiomerically pure compounds has found wide application for a variety of reactions over the last three decades. Despite the extensive developments in this area by many academic and industrial research groups, new auxiliary controlled reactions continue to evolve frequently [1]. First objectives in this area have been to develop chi...
متن کاملTitanium enolates of thiazolidinethione chiral auxiliaries: versatile tools for asymmetric aldol additions.
[formula: see text] Asymmetric aldol additions using chlorotitanium enolates of thiazolidinethione propionates proceed with high diastereoselectivity for the "Evans" or "non-Evans" syn product depending on the nature and amount of the base used. With (-)-sparteine as the base, selectivities of 97:3 to > 99:1 were obtained for the Evans syn products with 2 equivalents of base and for the non-Eva...
متن کاملHelicene-Based Chiral Auxiliaries and Chirogenesis
Helicenes are unique helical chromophores possessing advanced and well-controlled spectral and chemical properties owing to their diverse functionalization and defined structures. Specific modification of these molecules by introducing aromatic rings of differing nature and different functional groups results in special chiroptical properties, making them effective chiral auxiliaries and supram...
متن کاملApplication of chiral sulfoxides in asymmetric synthesis
Over the last three decades, the sulfinyl group has received considerable attention in asymmetric synthesis1‒5 as a chiral tool. The sulfinyl group is widely used as to bring about numerous asymmetric transformations. The effectiveness of the sulfoxide in diastereoselective auxiliary-induced reactions is mainly due to the steric and stereo electronic differences existing between the substituent...
متن کاملAsymmetric synthesis mediated by chiral ligands
Chiral chelated lithium amides were designed and synthesized. Studies have been done to explore the use of these lithium amides or their corresponding amines for enantioselective reactions such as deprotonation of prochiral cyclic ketones, kinetic resolution of racemic 2-substituted cyclohexanones by deprotonation, regioselective deprotonation of optically active 3-keto steroids, alkylation of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1996
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.54.564