Benefit of combining curcumin, harpagophytum and bromelain to reduce inflammation in osteoarthritic synovial cells

Purpose: Osteoarthritis is the most common cause of arthritis affecting millions people worldwide, characterized by joint pain, which a major driver clinical decision making and health service use. Initially considered as simple degenerative erosive process cartilage, concept has migrated from local cartilage problem caused wear tear, to complex disease involving inflammatory factors whole including synovium. In particular, synovial cells produce liberate into fluid numerous proteins involved in inflammation, pain or catabolism.