منابع مشابه
Behavioral teratology: overview.
The field of teratology has expanded in recent years to include the effects of prenatal insult on the function of postnatal animals. This broadening of teratology reflects an awareness of the need to look for more subtle manifestations of developmental toxicity than gross morphologic changes. One aspect of postnatal function which is receiving a great deal of attention is called behavioral tera...
متن کاملResearch strategies for behavioral teratology studies.
Several compelling aruguments have been advanced in support of expanding the use of "behavioral teratology" evaluations as routine components of toxicologic screening procedures. As a basis for development of effective behavioral teratology screening approaches, a conceptual framework is presented which interrelates: (1) changes in relative functional brain capacity with age, (2) possible times...
متن کامل[Present status of behavioral teratology in Japan].
The thalidomide catastrophe in 1959-1962 has given great impetus to the basic research interests in the adverse effects of various insults on germ cells, embryos, fetuses, and immature postnatal individuals. It has called further attention to behavioral ability to learn or respond appropriately to a changing environment in the offspring that are prenatally exposed to various insults, even thoug...
متن کاملBehavioral teratology of mercury and its compounds.
Mercury and its compounds have a wide spectrum of toxicities depending upon the chemical forms and modes of exposure. Among the various chemical forms, mercury vapor and methylmercury are well known and established as neurotoxic agents. Since the disasters in Minamata and Iraq, in which fetuses were more susceptible than adults to methylmercury exposure, much attention has been focused on prena...
متن کاملPredictiveness and limitations of test methods in teratology: overview.
Compounds intended for marketing by the pharmaceutical industry are tested for possible effects on reproductive processes in much the same way today as was carried out even before November 1961, when the drug thalidomide was related to human malformations. At that time, effects on male and female fertility were sought, but generally only for agents considered likely to alter the endocrinologic ...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1976
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.761873