Beclomethasone aerosol in childhood asthma

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Beclomethasone aerosol in childhood asthma.

Godfrey, S., and Konig, P. (1973). Archives of Disease in Childhood, 48, 665. Beclomethasone aerosol in childhood asthma. Twenty children have been treated with the steroid aerosol beclomethasone, half of them in an open trial and the other half in a controlled cross-over trial. Children were assessed by means of clinical examination, diary records, and twice-daily peak flow rate measurements m...

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Beclomethasone in childhood asthma.

It has not been possible so far to produce a systemic corticosteroid with anti-inflammatory effect on local tissues and without glucocorticoid action. However, esterification of the potent antiinflammatory steroid betamethasone with valeric acid in the 17 carbon position produced betamethasone-17-valerate (Betnovate*), a steroid with marked topical anti-inflammatory activity. Beclomethasone dip...

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Long-term beclomethasone dipropionate aerosol therapy in juvenile asthma.

Following a short-term clinical trial reported elsewhere, beclomethasone dipropionate aerosol has been given to 15 children with asthma for between 2 1/2 and 3 years except for a short placebo period after the first year. Month-by-month records of wheezing, peak flow rate, and other treatments used are presented for the first 17 months, adrenocortical function tests are reported for the first 2...

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beclomethasone dipropionate in the control of mild childhood asthma

The effects of controlling childhood asthma of the same daily dose (400 pg) of beclomethasone dipropionate, given in two or four equal divided doses from a metered aerosol, were compared in a double blind crossover study. Thirty one children aged 6-14 years completed the study. They had previously been shown to need beclomethasone by showing either symptoms or reduced peak flow when the treatme...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1973

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.48.9.665