Beclin1 Modulates Bone Homeostasis by Regulating Osteoclast and Chondrocyte Differentiation
نویسندگان
چکیده
منابع مشابه
RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis.
Osteolytic bone diseases, such as osteoporosis, are characterized by diminished bone quality and increased fracture risk. The therapeutic challenge remains to maintain bone homeostasis with a balance between osteoclast-mediated resorption and osteoblast-mediated formation. Osteoclasts are formed by the fusion of monocyte/macrophage-derived precursors. Here we report, to our knowledge for the fi...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2019
ISSN: 0884-0431,1523-4681
DOI: 10.1002/jbmr.3756