<b>Comparative analysis of allyl isothiocyanate (AITC)-induced carbohydrate oxidation changes </b><i><b>via</b></i><b> TRPV1 between mice and </b><b>chickens </b>
نویسندگان
چکیده
منابع مشابه
Intragastric administration of allyl isothiocyanate increases carbohydrate oxidation via TRPV1 but not TRPA1 in mice.
The transient receptor potential (TRP) channel family is composed of a wide variety of cation-permeable channels activated polymodally by various stimuli and is implicated in a variety of cellular functions. Recent investigations have revealed that activation of TRP channels is involved not only in nociception and thermosensation but also in thermoregulation and energy metabolism. We investigat...
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چکیده ندارد.
Mechanisms of transient receptor potential vanilloid 1 activation and sensitization by allyl isothiocyanate.
Allyl isothiocyanate (AITC; aka, mustard oil) is a powerful irritant produced by Brassica plants as a defensive trait against herbivores and confers pungency to mustard and wasabi. AITC is widely used experimentally as an inducer of acute pain and neurogenic inflammation, which are largely mediated by the activation of nociceptive cation channels transient receptor potential ankyrin 1 and trans...
متن کاملAllyl isothiocyanate as a cancer chemopreventive phytochemical.
Allyl isothiocyanate (AITC), which occurs in many common cruciferous vegetables, is widely and often frequently consumed by humans. Besides antimicrobial activity against a wide spectrum of pathogens, it showed anticancer activity in both cultured cancer cells and animal models, although the underlining mechanisms remain largely undefined. Bioavailability of AITC is extremely high, as nearly 90...
متن کاملTRPA1 agonists--allyl isothiocyanate and cinnamaldehyde--induce adrenaline secretion.
Thermosensitive transient receptor potential (TRP) channels, especially TRPV1 and TRPA1, are activated by the pungent compounds present in spices. TRPV1 activation by the intake of capsaicin, the irritant in hot pepper, induces adrenaline secretion and increases energy consumption. TRPV1 is mainly expressed in the sensory neurons and coexpressed with TRPA1 at a high frequency. However, the mech...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 2017
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.38.149