Bcl-2 mediates induction of neural differentiation
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چکیده
منابع مشابه
Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonal stem cells
We report here that all trans-retinoic acid (RA), a classical morphogen, induces apoptosis during the neural differentiation of the embryonic stem cell line P19. The apoptotic cells showed, in addition to DNA cleavage, typical morphological changes including chromatin condensation, nuclear fragmentation, and cytoplasmic vacuolation. These apoptotic changes became obvious by 12 h after the addit...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2003
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1206844