Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study
نویسندگان
چکیده
منابع مشابه
prevalence of atopic dermatitis in children with type 1 diabetes mellitus in southeastern of iran (kerman province): a case-control study
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15 صفحه اولBayesian Inference for Matched Case-Control Studies
Case-control studies occupy a central place in epidemiological research. The basic idea here is the comparison of a group (the “cases”) having the outcome of interest (normally some disease) with respect to a control group (those without disease) regarding one or more characteristics (exposure to certain external events). One of the early examples, which sparked a lot of debate in the fifties b...
متن کاملCompare the Relative Frequency of Thyroid Function Disorders in Obese and Overweight Children with Non-Obese Children; a Case-Control Study
BackgroundChildhood obesity has become a global epidemic. In the recent studies has reported risk of thyroid dysfunction due to obesity. Therefore, this study intends to compare the relative frequency of thyroid function disorders in obese and overweight children with non-obese children.Materials and MethodsThis case-control study during 2015 to 2016 in Birjand, Iran was done on 137 children an...
متن کاملVancomycin pharmacokinetics in normal and morbidly obese subjects.
In an uncontrolled study, vancomycin pharmacokinetics were determined in four normal (total body weight [TBW], 65.9 to 89.1 kg) and six morbidly obese (TBW, 111.4 to 226.4 kg) subjects. The morbidly obese subjects were investigated 3 to 4 h after gastric bypass surgery. Mean terminal half-lives, volumes of distribution, and total body clearances for the normal controls and the morbidly obese (T...
متن کاملPharmacokinetics of Antimicrobials in Obese Children.
INTRODUCTION Childhood obesity is common and results in substantial morbidity. The most commonly prescribed drugs in obese children are antibiotics. However, physiologic changes associated with childhood obesity can alter antibiotic pharmacokinetics and optimal body size measures to guide dosing in his population are ill defined. This combination can result in therapeutic failures or drug-relat...
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ژورنال
عنوان ژورنال: Clinical Therapeutics
سال: 2015
ISSN: 0149-2918
DOI: 10.1016/j.clinthera.2015.05.006