Banking Human Induced Pluripotent Stem Cells: Lessons Learned from Embryonic Stem Cells?
نویسندگان
چکیده
منابع مشابه
Embryonic Stem Cells/induced Pluripotent Stem Cells
Understanding the regulation of cell-cell interactions during the formation of compact myocardial structures is important for achieving true cardiac regeneration through enhancing the integration of stem cell-derived cardiomyocytes into the recipient myocardium. In this study, we found that cellular repressor of E1A-stimulated genes 1 (CREG1) is highly expressed in both embryonic and adult hear...
متن کاملLarge-Scale Expansion of Human Embryonic and Induced Pluripotent Stem Cells for Cell Therapy Applications
Successful isolation, derivation and culturing of human pluripotent stem cells, including human embryonic stem cells (hESCs) and human induced pluripotent stem (hiPSCs) cells in laboratory scale has opened new horizones for cell therapy applications such as tissue engineering and regenerative medicine. However, most of the cell therapy protocols using these unique cells require large number of ...
متن کاملInduced Pluripotent Stem Cells: Challenges and Opportunities
Regenerative capacity of mammals is limited and can rarely regenerate a specific organ or tissue fully. Due to these limitations, regenerative medicine seeks efficient and safe cell sources for regeneration of damaged tissues and organs or treatment for incurable diseases. Human embryonic stem cells (HESCs) hold two important properties called self renewal and pluripotency. However, the use of ...
متن کاملEmbryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells Chemically Induced Specification of Retinal Ganglion Cells From Human Embryonic and Induced Pluripotent Stem Cells
The loss of retinal ganglion cells (RGCs) is the primary pathological change formany retinal degenerative diseases.Althoughthere is currentlynoeffective treatment for this groupofdiseases, cell transplantation to replace lost RGCs holds great potential. However, for the development of cell replacement therapy, better understanding of themolecular details involved in differentiating stemcells in...
متن کاملMaintaining Embryonic Stem Cells and Induced Pluripotent Stem Cells
Early in 1981, the pluripotential cells were first established from mouse embryos by Evans et al (Evans and Kaufman, 1981). In the same year, Martin et al (Martin, 1981) named these pluripotential cells embryonic stem (ES) cells. In 1990s, human ES cells were first established by Thomson et al (Thomson et al., 1998). Such ES cells isolated from inner cell masses of blastocysts present the uniqu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2013
ISSN: 1934-5909
DOI: 10.1016/j.stem.2013.09.007