Balancing Genetics (Science) and Counseling (Art) in Prenatal Chromosomal Microarray Testing
نویسندگان
چکیده
منابع مشابه
Chromosomal microarray versus karyotyping for prenatal diagnosis.
BACKGROUND Chromosomal microarray analysis has emerged as a primary diagnostic tool for the evaluation of developmental delay and structural malformations in children. We aimed to evaluate the accuracy, efficacy, and incremental yield of chromosomal microarray analysis as compared with karyotyping for routine prenatal diagnosis. METHODS Samples from women undergoing prenatal diagnosis at 29 c...
متن کاملVoluntary HIV counseling and testing during prenatal care in Brazil.
OBJECTIVE Voluntary HIV counseling and testing are provided to all Brazilian pregnant women with the purpose of reducing mother-to-child HIV transmission. The purpose of the study was to assess characteristics of HIV testing and identify factors associated with HIV counseling and testing. METHODS A cross-sectional study was carried out comprising 1,658 mothers living in Porto Alegre, Brazil. ...
متن کاملThe Use of Chromosomal Microarray Analysis in Prenatal Diagnosis.
Chromosomal microarray analysis (CMA) identifies microdeletions and duplications undetected on karyotype analysis. Copy number variants (CNVs) occur in 1% to 1.7% of all pregnancies, with clinical implications. All women undergoing invasive testing for routine indications should be offered microarray. Clinically significant CNVs are seen in approximately 6% of pregnancies with ultrasound anomal...
متن کاملClinical implementation of chromosomal microarray technology in prenatal diagnosis. (Review).
Chromosomal microarray technology represents the technical convergence of molecular genetics and cytogenetics, and is rapidly revolutionizing modern cytogenetics. Expected genomic aberrations are accurately identified and provide readily interpretable results that are suitable for clinical risk stratification and therapeutic strategies. The applic...
متن کاملOrganizational predictors of prenatal HIV counseling and testing.
OBJECTIVES Efforts to prevent perinatal transmission of HIV include implementation of prenatal counseling and testing programs. The objective of this study was to assess organizational predictors of HIV counseling and testing. METHODS Surveillance records were collected on 5900 prenatal patients from 9 hospital and community clinics in Connecticut. RESULTS Some organizational factors (e.g.,...
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ژورنال
عنوان ژورنال: Journal of Genetic Counseling
سال: 2016
ISSN: 1059-7700,1573-3599
DOI: 10.1007/s10897-016-9966-5