Bacterial contact-dependent growth inhibition
نویسندگان
چکیده
منابع مشابه
Functional Characterization of Pseudomonas Contact Dependent Growth Inhibition (CDI) Systems
Contact-dependent inhibition (CDI) toxins, delivered into the cytoplasm of target bacterial cells, confer to host strain a significant competitive advantage. Upon cell contact, the toxic C-terminal region of surface-exposed CdiA protein (CdiA-CT) inhibits the growth of CDI- bacteria. CDI+ cells express a specific immunity protein, CdiI, which protects from autoinhibition by blocking the activit...
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UNLABELLED Bacteria that express contact-dependent growth inhibition (CDI) systems outcompete siblings that lack immunity, suggesting that CDI mediates intercellular competition. To further explore the role of CDI in competition, we determined the target cell range of the CDIEC93 system from Escherichia coli EC93. The CdiAEC93 effector protein recognizes the widely conserved BamA protein as a r...
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ژورنال
عنوان ژورنال: Trends in Microbiology
سال: 2013
ISSN: 0966-842X
DOI: 10.1016/j.tim.2013.02.003