Bacteria acting with tumorigenic chaperones
نویسندگان
چکیده
منابع مشابه
Multitasking SecB chaperones in bacteria
Protein export in bacteria is facilitated by the canonical SecB chaperone, which binds to unfolded precursor proteins, maintains them in a translocation competent state and specifically cooperates with the translocase motor SecA to ensure their proper targeting to the Sec translocon at the cytoplasmic membrane. Besides its key contribution to the Sec pathway, SecB chaperone tasking is critical ...
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Polypeptides exiting the ribosome must fold and assemble in the crowded environment of the cell. Chaperones and other protein homeostasis factors interact with newly translated polypeptides to facilitate their folding and correct localization. Despite the extensive efforts, little is known about the specificity of the chaperones and other factors that bind nascent polypeptides. To address this ...
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ژورنال
عنوان ژورنال: Protoplasma
سال: 2019
ISSN: 0033-183X,1615-6102
DOI: 10.1007/s00709-019-01352-8