Baclofen Intoxication

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منابع مشابه

[Electroencephalographic burst-suppression pattern due to baclofen intoxication].

berg A, et al. Diagnosis and management of out-of-hospital cardiac arrest secondary to coronary artery spasm. Resuscitation. 2003;58:145-52. 2. Karch SB. Coronary artery spasm induced by intravenous epi-nephrine overdose. High dose nitroglycerin treatment in a patient with cardiac arrest: a case report. A. Recurrent catecholamine-induced coronary vasospam treated by intracoronary injection of i...

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Baclofen intoxication after accidental ingestion in a 3-year-old child

Baclofen is a skeletal muscle relaxant, used to control spasticity in both adults and children with neuromuscular disorders. Several cases of baclofen overdose have been reported, but only a small number have involved children. We report a 3-year-old girl with accidental ingestion of baclofen, who presented with coma, bradycardia and hypotension. She recovered within 24 hours with supportive tr...

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Baclofen overdose.

A 57-year-old woman suffering from multiple sclerosis took an estimated 1500 mg of baclofen. She became deeply unconscious with generalized flaccid muscle paralysis and absent tendon reflexes. Toxicological analysis confirmed the presence of baclofen together with small amounts of paracetamol and glutethimide. Supportive therapy, including assisted ventilation for 3 days, led to complete recove...

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Massive baclofen overdose.

A case is presented of a massive baclofen overdose with the highest blood baclofen concentrations currently reported. Interesting clinical features included profound hypotension, distributive shock and absent brainstem reflexes. Cerebral recovery was surprisingly slow but complete, and was then unexpectedly terminated by a sudden major splenic arterial haemorrhage followed by a severe haemorrha...

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Abuse Liability of Baclofen

TO THE EDITOR I read with interest the case report on baclofen abuse by Ghosh and Bhuyan in May issue of Clinincal Psychopharmacology and Neuroscience 2017. The patient reportedly was prescribed quetiapine 100 mg, escitalopram 20 mg, mirtazapine 15 mg, lorazepam 2 mg and baclofen 20 mg after initial detoxification, for depression and insomnia along with relapse prevention. As mentioned, escital...

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ژورنال

عنوان ژورنال: Türk Yoğun Bakım Derneği Dergisi

سال: 2015

ISSN: 2146-6416

DOI: 10.4274/tybdd.86580