B005 Angiotensinogen gene polymorphism and lipoprotein profile in essential hypertensive patients

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T+31C polymorphism of angiotensinogen gene and essential hypertension.

A common variant at codon 235 of the angiotensinogen gene with methionine to threonine amino acid substitution (AGT M235T) has been reported as a genetic risk for essential hypertension. However, the frequency of AGT T235 was heterogeneous among races, and a positive association between AGT M235T and hypertension was not settled. To examine the association in a general population of Japanese (n...

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T131C Polymorphism of Angiotensinogen Gene and Essential Hypertension

A common variant at codon 235 of the angiotensinogen gene with methionine to threonine amino acid substitution (AGT M235T) has been reported as a genetic risk for essential hypertension. However, the frequency of AGT T235 was heterogeneous among races, and a positive association between AGT M235T and hypertension was not settled. To examine the association in a general population of Japanese (n...

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Lipoprotein lipase gene polymorphism and lipid profile in patients with hypertriglyceridemia.

AIM To assess lipid profile and the genotype distribution of lipoprotein lipase gene polymorphism at Pvu II polymorphic site within the intron between exons 6 and 7 in patients with hypertriglyceridemia. METHODS Pvu II polymorphism was determined in 116 hypertriglyceridemic patients and 50 normolipidemic controls from Zagreb, Croatia. DNA was extracted from peripheral blood mononuclear cells....

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Association of TNF-α G308A gene polymorphism in essential hypertensive patients without type 2 diabetes mellitus.

This study aims to investigate the effects of tumor necrosis factor alpha (TNF-α) G308A gene polymorphism on essential hypertension (EHT) with or without type 2 diabetes mellitus (T2DM). The project was conducted on buccal epithelial and blood cells for case and control patients, respectively. Epithelial cells were obtained from the inner part of the cheeks. Techniques including DNA extraction,...

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The recently published paper entitled “Genetic and adverse health outcome associations with treatment resistant hypertension in GenHAT” by Lynch et al. [1] evaluated the association between 78 candidate gene polymorphisms and treatment resistant hypertension (TRH). Interestingly, the main finding was the association of two genetic variants in the angiotensinogen (AGT) gene, the M allele of rs69...

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ژورنال

عنوان ژورنال: American Journal of Hypertension

سال: 1998

ISSN: 0895-7061

DOI: 10.1016/s0895-7061(97)90848-7