B-type natriuretic peptide: a simple new test to identify coronary artery disease?

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A rteries stiffen with age, largely as a consequence of structural alteration of the collagen and elastin content of the artery wall. Circulating B-type natriuretic peptide (BNP), secreted predominantly from the heart, also increases with age, probably as a consequence of left ventricular wall stress induced by a rise in impedance to ejection or structural changes in the myocardium including ag...

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Coronary angiography transiently increases plasma pro-B-type natriuretic peptide.

AIMS Increased plasma concentrations of B-type natriuretic peptide (BNP) and its precursor (proBNP) provide important prognostic information in patients presenting with acute coronary syndromes. Although a majority of these patients undergo early invasive assessment, the effects of coronary angiography per se on plasma BNP and proBNP concentrations are not known. We therefore sought to determin...

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The structure of the mouse natriuretic peptide type-B (BNP) gene was determined by isolating and sequencing genomic clones. The mouse BNP gene was structurally similar to other natriuretic peptide genes and comprised three exons and two introns. Expression of the mouse BNP gene was found only in cardiac tissue as determined by ribonuclease protection analyses. Initiation of transcription was 31...

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Evaluation of a new, rapid bedside test for quantitative determination of B-type natriuretic peptide.

References 1. Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). JAMA 1993;269:3015–23. 2. British Cardiac Society, British Hyperlipidaemia Association, British...

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ژورنال

عنوان ژورنال: QJM: An International Journal of Medicine

سال: 2005

ISSN: 1460-2393,1460-2725

DOI: 10.1093/qjmed/hci111