Axonally Translated SMADs Link Up BDNF and Retrograde BMP Signaling
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چکیده
منابع مشابه
Axonally Translated SMADs Link Up BDNF and Retrograde BMP Signaling
Axonal target-derived BMP and neurotrophin signaling are both known to regulate neuronal gene expression, differentiation, and axon growth. In this issue of Neuron, Ji and Jaffrey (2012) discovered that BMP-signaling endosomes depend on BDNF-induced axonal synthesis of SMADs to retrogradely regulate transcription in developing trigeminal neurons, providing a mechanism of integrating the two tar...
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ژورنال
عنوان ژورنال: Neuron
سال: 2012
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2012.03.012