Avoidable Adverse Events Related to Ignoring the Do-Not-Do Recommendations

Opioid-related adverse drug events: do parents recognize the signals?

OBJECTIVES Evidence of unrelieved childhood pain, adverse drug events (ADE), and deaths suggest that parents may inadequately respond to pain and opioid-related ADE signals. This study examined parents' recognition and response to pain and ADE signals using both dynamic hypothetical scenarios and real at-home opioid decisions. MATERIALS AND METHODS A total of 514 parents whose children requir...

Do We Know What We Do not Know? A Response to Celine Bonnet

Performance of electrophysiologic study in an asymptomatic patient with type 2 intermittent Brugada syndrome: To do or not to do?

Background: Brugada syndrome (BrS) is an inherited channelopathy, which is associated with sudden cardiac death due to rapid polymorphic VT or VF. There is no definite consensus regarding the management of asymptomatic patients. Some experts advocate close follow-up; others propose the programmed stimulation for risk stratification. We aimed to evaluate the benefit of complete atrial and ventri...

Do Patient Preferences Influence Surgeon Recommendations for Treatment?

Background: When the best treatment option is uncertain, a patient’s preference based on personal values should bethe source of most variation in diagnostic and therapeutic interventions. Unexplained surgeon-to-surgeon variation intreatment for hand and upper extremity conditions suggests that surgeon preferences have more influence than patientpreferences.Methods: A total of 184 surgeons revie...

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Design a clocked synchronous state machine with four inputs, G1–G4, that are connected to pushbuttons. The machine has four outputs, L1–L4, connected to lamps or LEDs located near the like-numbered pushbuttons. There is also an ERR output connected to a red lamp. In normal operation, the L1–L4 outputs display a 1-out-of-4 pattern. At each clock tick, the pattern is rotated by one position; the ...