Avastin Saga Reveals Debate Over Clinical Trial Endpoints
نویسندگان
چکیده
منابع مشابه
IPF clinical trial design and endpoints
PURPOSE OF REVIEW There remains a dire need for therapies that impact the clinical course of patients with idiopathic pulmonary fibrosis (IPF). Indeed, there is a surge of interest in IPF therapeutics, with many candidate agents in various stages of development. Optimal design and implementation of the appropriate prospective clinical trials are essential to demonstrate clinical efficacy of pro...
متن کاملClinical Trial Endpoints in Acute Kidney Injury
The development and use of consensus criteria for acute kidney injury (AKI) diagnosis and the inclusion of recently identified markers of renal parenchymal damage as endpoints in clinical trials have improved the ability of physicians to compare the incidence and severity of AKI across patient populations, provided targets for testing new treatments, and may increase insight into the mechanisms...
متن کاملClinical trial endpoints in acute kidney injury.
The development and use of consensus criteria for acute kidney injury (AKI) diagnosis and the inclusion of recently identified markers of renal parenchymal damage as endpoints in clinical trials have improved the ability of physicians to compare the incidence and severity of AKI across patient populations, provided targets for testing new treatments, and may increase insight into the mechanisms...
متن کاملClinical Trial Endpoints in Acute Kidney Injury
The development and use of consensus criteria for acute kidney injury (AKI) diagnosis and the inclusion of recently identified markers of renal parenchymal damage as endpoints in clinical trials have improved the ability of physicians to compare the incidence and severity of AKI across patient populations, provided targets for testing new treatments, and may increase insight into the mechanisms...
متن کاملClinical Trial Endpoints in Acute Kidney Injury
The development and use of consensus criteria for acute kidney injury (AKI) diagnosis and the inclusion of recently identified markers of renal parenchymal damage as endpoints in clinical trials have improved the ability of physicians to compare the incidence and severity of AKI across patient populations, provided targets for testing new treatments, and may increase insight into the mechanisms...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2012
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djs265