Autosomal dominant mesomandibular fibro-osseous dysplasia: a self-resolving inherited fibro-osseous lesion of the jaws

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Autosomal dominant mesomandibular fibro-osseous dysplasia: a self-resolving inherited fibro-osseous lesion of the jaws

A hereditary congenital condition characterized by a fibro-osseous lesion sharing some features with fibrous dysplasia and affecting the middle aspect of the mandible is presented. The condition was initially described as congenital monostotic fibrous dysplasia in two siblings, a male and a female. However, there is sufficient evidence that the disorder is autosomal dominant since it has been e...

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Fibro-osseous lesions compose woven or immature bone formed by benign proliferation of spindle cells. Based on radiographic and histologic features, these lesions are grouped into many specifi c entities.[1] The overlapping histological and confusing nomenclature can be simplifi ed by their radiographic presentation. They are clearly defi ned by their pattern in plain radiograph or in computed ...

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ژورنال

عنوان ژورنال: Frontiers in Physiology

سال: 2012

ISSN: 1664-042X

DOI: 10.3389/fphys.2012.00458