Autophagy, a double-edged sword in hepatocarcinogenesis
نویسندگان
چکیده
منابع مشابه
Autophagy, a double-edged sword in hepatocarcinogenesis
Autophagy has opposite effects on hepatocarcinogenesis depending on whether it occurs before or after its onset. Autophagy prevents the initiation of hepatocarcinogenesis by suppressing oxidative stress and DNA damage. However, it also inhibits cell death and the expression of tumor suppressors to promote tumor progression once hepatocarcinogenesis has been initiated.
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ژورنال
عنوان ژورنال: Molecular & Cellular Oncology
سال: 2015
ISSN: 2372-3556
DOI: 10.1080/23723556.2015.1004968