Automatic quantification of microvessel density in urinary bladder carcinoma

Angiogenesis in urinary bladder carcinoma as defined by microvessel density (MVD) after immunohistochemical staining for Factor VIII and CD31

BACKGROUND Among the patients with bladder cancer, a group is still at risk of disease recurrence, progression, and death from their cancer after curative treatment. Angiogenesis is a crucial pathogenic mechanism for this type of urothelial carcinoma and is a potential therapeutic target. OBJECTIVES To quantify tumor angiogenesis in bladder cancer and determine whether it correlates with tumo...

Evaluation of the prognostic value of CD117 and CK20 biomarkers in urinary bladder carcinoma

Background: Over-expression of CD117 and cytokeratin 20 (CK20) is seen in many malignancies. Given that few studies have been conducted regarding the role of these biomarkers in the etiology of bladder tumours, this study aimed to evaluate the prognostic value of CD117 and CK 20 biomarkers in the benign and malignant tumours of urinary bladder carcinoma. Methods: This case-control study was co...

Relationship between grade and MDM2 oncoprotein overexpression in transitional cell carcinoma of the urinary bladder

Objective: Transitional cell carcinoma (TCC) of the urinary bladder is the second common cancer of the genitourinary tract. Several parameters such as clinical and pathological parameters, molecular factors, and etc play a role in determination of prognosis and type of treatment. In this research study, ...

Epidermoid Carcinoma of Urinary Bladder

Carcinoma of the Urinary Bladder

Aims: To determine costs and factors related to the total costs of cystectomy. To study the results of the radiological examinations performed 7-14 days after a cystectomy. To investigate if a single instillation of epirubicin after transurethral resection (TUR) may influence the time to the first recurrence and its size. To elucidate if a routine with reduced numbers of follow-up cystoscopies ...