Autoimmune Neurological Conditions Associated With Zika Virus Infection

Neurological manifestations of Zika virus infection

Zika virus (ZIKV) is a flavivirus (Flaviviridae family) transmitted mainly by Aedes mosquitoes. The virus was restricted to the African continent until its spread to south-east Asia in the 1980's, the Micronesia in 2007, the French Polynesia in 2013 and, more recently in the Americas in 2015, where, up to date, the World Health Organization (WHO) has estimated about 3-4 million total cases of Z...

Zika Virus Infection Associated With Severe Thrombocytopenia.

We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia.

Zika Virus Infection after Returning from Thailand

zika virus infection

Bilateral posterior uveitis associated with Zika virus infection.

A 26-year-old healthy white man returned to Washington, DC, from visiting Puerto Rico, in June, 2016. The day after his return he developed chills, myalgia, arthralgia, and a centrifugal skin rash, and was given a diagnosis of Zika virus infection by his physician, confi rmed by realtime PCR (RT-PCR) assay (US Centers for Disease Control and Prevention [CDC]) on a serum specimen taken on the fi...