Autoimmune hematologic complications of umbilical cord blood transplantation

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Umbilical cord blood transplantation for the treatment of hematologic malignancies.

BACKGROUND The use of unrelated umbilical cord blood (UCB) has grown as an allogeneic source of hematopoietic cells for transplantation of patients with hematologic malignancies. As the number of UCB transplantation procedures has grown, an increasing number of publications have focused on disease-specific outcomes. METHODS This review focuses on the outcome data following UCB transplantation...

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Umbilical cord blood transplantation

Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disp...

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Umbilical cord blood transplantation.

Umbilical cord blood transplantation (CBT) has been widely used as an alternative source of hematopoietic cell support for stem cell transplant patients. CBT offers several advantages over traditional stem cell sources, such as immediate availability, absence of risk for donors, lower risk of acute graft-versus-host disease, and a less stringent requirement for human leukocyte antigen matching....

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Umbilical cord blood transplantation.

Interest in umbilical cord blood as an alternative source of hematopoietic stem cells is growing rapidly. Umbilical cord blood offers the clinician a source of hematopoietic stem cells that are readily available and rarely contaminated by latent viruses. Moreover, the collection of umbilical cord blood poses no risk to the donor; there is no need for general anesthesia or blood replacement, and...

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ژورنال

عنوان ژورنال: Hematology/Oncology and Stem Cell Therapy

سال: 2021

ISSN: 1658-3876

DOI: 10.1016/j.hemonc.2020.07.009