Autoerythrocyte Sensitization A Form of Purpura Producing Painful Bruising Following Autosensitization to Red Blood Cells in Certain Women

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Autoerythrocyte Sensitization or Psychogenic Purpura?

The above quotation is taken from the original clinical report in which Gardner and Diamond (1955) described the syndrome of autoerythrocyte sensitization as an unusual purpuric syndrome in which crops of apparently spontaneous painful inflammatory ecchymoses occurred in four women who had sustained physical injury shortly before the onset of symptoms. They postulated that, as a result, their p...

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An Extremely Rare Cause of Bruising in Children: Autoerythrocyte Sensitization Syndrome

Autoerythrocyte sensitization syndrome (ASS)—also known as Gardner-Diamond syndrome—is an autoimmune vasculopathy associated with sensitization to phosphatidylserine, a phosphoglyceride of red blood cell membranes [1]. The syndrome was first described in 1955 by Gardner and Diamond in 4 female patients [2]. ASS is typically seen in adult females; however, pediatric and male patients have also b...

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Autoerythrocyte sensitization syndrome presenting with general neurodermatitis

Autoerythrocyte sensitization syndrome (AES) was first described by Gardner and Diamond in 1955, when four women with painful bruising were depicted. Patients with AES typically present with the development of recurrent, spontaneous, painful ecchymosis, frequently preceded by a prodrome of pain or itching of the skin. The patients are sensitive to their own red blood cells injected intradermall...

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AUTOERYTHROCYTE SENSITIZATION SYNDROME: REPORT OF A CASE AND REVIEW OF THE LITERATURE

Autoerythrocyte sensitization syndrome CABS) is a rare purpuric disorder of women characterized by inflammatory and painful ecchymotic lesions unrelated to blood clotting or vascular abnormalities. Gastrointestinal bleeding, hematuria, headache or syncopal attacks may also be observed. Our patient is a 33-year-old woman presenting with recurrent severe painful ecchymotic lesions on both lo...

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Autoerythrocyte Sensitization Syndrome Presenting with General Neurodermatitis: Factitious Purpura or Psychophysiological Entity?

Autoerythrocyte sensitization syndrome (AES) is a disorder characterized by recurrent, spontaneous, painful bruising in patients with underlying psychosis and neurosis. Its pathogenesis is uncertain. Purpuric lesions reproduced by injections of washed autologous erythrocytes suggest an autoimmune etiology. The authors described a 50-year-old woman who presented with recurrent episodes of painfu...

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ژورنال

عنوان ژورنال: Blood

سال: 1955

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v10.7.675.675